Immunity anniversary: antibodies against SARS-CoV-2 remain one year after infection

A study co-directed by ISGlobal found that about 97% of the monitored health workers remain seropositive after twelve and a half months of their infection.

Over 12 months, researchers monitored the antibodies of the health personnel. Photo by Mufid Majnun on Unsplash

A study co-led by the Barcelona Institute for Global Health (ISGlobal) analyzed the presence of antibodies in healthcare personnel who were infected with SARS-CoV-2 more than a year ago and proved that immunity is long-lasting.

The project started in the first wave of the SARS-CoV-2 pandemic and it followed 173 workers from primary care centers in Catalonia that had been infected, carrying out serology analyses over the months:

  • At 9 months, 92.4% were still seropositive (90% had IgG, 76% IgA, and 61% specific IgM)
  • In April 2021 (after approximately one year from the start of the study), 96.88% of the 64 workers who had not yet been vaccinated were still seropositive (95.31% IgG, 82.81% IgA)

“Considering that the antibody levels achieved upon vaccination are usually higher than those generated upon natural infection, our results suggest that vaccine-induced immunity will also be long-lasting”
Carlota Dobaño, ISGlobal, first co-author of the study.

With the results that show that the IgG remain stable, the hope of a long-lasting immunity thanks to the COVID-19 vaccine increases.

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