{"id":51941,"date":"2026-07-06T12:25:58","date_gmt":"2026-07-06T10:25:58","guid":{"rendered":"https:\/\/ellipse.prbb.org\/?p=51941"},"modified":"2026-07-06T13:07:03","modified_gmt":"2026-07-06T11:07:03","slug":"un-programa-immunitari-ancestral-mes-antic-que-els-animals","status":"publish","type":"post","link":"https:\/\/ellipse.prbb.org\/ca\/un-programa-immunitari-ancestral-mes-antic-que-els-animals\/","title":{"rendered":"Un programa immunitari ancestral m\u00e9s antic que els animals"},"content":{"rendered":"\n

El sistema immunitari \u00e9s una de les grans innovacions de la vida animal. Per\u00f2 part del programa gen\u00e8tic que el fa possible podria ser molt m\u00e9s antic que els mateixos animals.<\/p>\n\n\n\n

Un estudi liderat per la Universitat de Kyoto i l\u2019Institut de Biologia Evolutiva<\/a> (IBE, CSIC-UPF)<\/strong> ha reconstru\u00eft la hist\u00f2ria evolutiva dels llinatges de c\u00e8l\u00b7lules sangu\u00ednies<\/a> comparant quins gens estan actius en organismes molt distants, des de mam\u00edfers i peixos zebra fins a esponges i parents unicel\u00b7lulars dels animals.<\/p>\n\n\n\n

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\"Infografia<\/figure>\n\n\n\n
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Els resultats, publicats a PNAS<\/em><\/a>, suggereixen que l\u2019evoluci\u00f3 no va inventar la immunitat animal des de zero. En canvi, va reutilitzar i reorganitzar programes cel\u00b7lulars antics per donar lloc a noves funcions.<\/p>\n\n\n\n

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\"Infografia<\/figure>\n\n\n\n
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Idees clau<\/h2>\n\n\n\n
  • Les primeres c\u00e8l\u00b7lules sangu\u00ednies probablement eren similars als macr\u00f2fags<\/strong>
    L\u2019estudi suggereix que les c\u00e8l\u00b7lules sangu\u00ednies m\u00e9s antigues eren c\u00e8l\u00b7lules m\u00f2bils i defensives, semblants als macr\u00f2fags actuals.<\/li>
  • Aquest programa podria ser anterior als animals<\/strong>
    Les primeres c\u00e8l\u00b7lules sangu\u00ednies similars a c\u00e8l\u00b7lules immunit\u00e0ries podrien haver aparegut fa uns 700 milions d\u2019anys, durant la transici\u00f3 cap a la vida multicel\u00b7lular.<\/li>
  • Fos sembla ser un gen clau<\/strong>
    El gen Fos<\/em> podria haver ajudat a regular aquest programa protector ancestral, reutilitzant eines gen\u00e8tiques ja presents en ancestres unicel\u00b7lulars.<\/li>
  • El desenvolupament de la sang encara conserva traces evolutives<\/strong>
    L\u2019hematopo\u00e8si moderna podria reflectir encara l\u2019ordre en qu\u00e8 van emergir els diferents tipus de c\u00e8l\u00b7lules sangu\u00ednies durant l\u2019evoluci\u00f3.<\/li><\/ul>\n\n\n\n
    <\/div>\n\n\n\n

    <\/p>\n\n\n\n

    <\/div>\n","protected":false},"excerpt":{"rendered":"

    Un estudi liderat per la Universitat de Kyoto i l\u2019IBE reconstrueix la hist\u00f2ria evolutiva de les c\u00e8l\u00b7lules sangu\u00ednies i suggereix que les primeres c\u00e8l\u00b7lules similars a c\u00e8l\u00b7lules immunit\u00e0ries van emergir fa uns 700 milions d\u2019anys.<\/p>\n","protected":false},"author":37,"featured_media":51942,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[26],"tags":[283,211,411,568],"new-type":[35],"class_list":["post-51941","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-recerca","tag-evolucio","tag-ibe-csic-upf","tag-immunologia","tag-sang","new-type-noticies"],"acf":[],"_links":{"self":[{"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/posts\/51941","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/users\/37"}],"replies":[{"embeddable":true,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/comments?post=51941"}],"version-history":[{"count":12,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/posts\/51941\/revisions"}],"predecessor-version":[{"id":51992,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/posts\/51941\/revisions\/51992"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/media\/51942"}],"wp:attachment":[{"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/media?parent=51941"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/categories?post=51941"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/tags?post=51941"},{"taxonomy":"new-type","embeddable":true,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/new-type?post=51941"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}