{"id":19179,"date":"2020-11-23T21:56:34","date_gmt":"2020-11-23T20:56:34","guid":{"rendered":"https:\/\/ellipse.prbb.org\/?p=19179"},"modified":"2020-12-16T17:31:46","modified_gmt":"2020-12-16T16:31:46","slug":"una-base-de-dades-de-genomes-de-bacteris-i-els-seus-hostes-pel-desenvolupament-dantibiotics","status":"publish","type":"post","link":"https:\/\/ellipse.prbb.org\/ca\/una-base-de-dades-de-genomes-de-bacteris-i-els-seus-hostes-pel-desenvolupament-dantibiotics\/","title":{"rendered":"Una base de dades de genomes de bacteris i els seus hostes pel desenvolupament d&#8217;antibi\u00f2tics"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">El <a rel=\"noreferrer noopener\" href=\"http:\/\/www.crg.eu\/\" target=\"_blank\">Centre de Regulaci\u00f3 Gen\u00f2mica (CRG)<\/a> ha participat en la <a href=\"https:\/\/www.crg.eu\/en\/news\/new-database-measures-gene-activity-bacteria-and-their-human-hosts#S2\" target=\"_blank\" rel=\"noreferrer noopener\">recent creaci\u00f3<\/a> de <a rel=\"noreferrer noopener\" href=\"http:\/\/www.tartaglialab.com\/dualseq\/\" target=\"_blank\">DualSeqDB<\/a>, una base de dades amb informaci\u00f3 sobre com els pat\u00f2gens i els seus hostes naturals canvien la seva expressi\u00f3 g\u00e8nica durant el proc\u00e9s d&#8217;infecci\u00f3.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">La base de dades cont\u00e9 els resultats de la <strong><a href=\"https:\/\/ellipse.prbb.org\/ca\/noves-eines-per-a-millorar-lanalisi-de-la-sequencia-i-estructura-del-genoma\/\" target=\"_blank\" rel=\"noreferrer noopener\">seq\u00fcenciaci\u00f3 massiva<\/a> i simult\u00e0nia del <a href=\"https:\/\/ellipse.prbb.org\/ca\/microomics-sequenciacio-dultima-generacio-per-analitzar-el-microbioma\/\" target=\"_blank\" rel=\"noreferrer noopener\">genoma de diferents bacteris<\/a> i els seus hostes durant una infecci\u00f3.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Amb aquestes dades, d&#8217;acc\u00e9s obert, la comunitat cient\u00edfica podria <strong>identificar els gens<\/strong> que utilitzen els diferents tipus de <a href=\"https:\/\/ellipse.prbb.org\/ca\/demostren-que-els-bacteris-poden-emmagatzemar-informacio-de-manera-similar-a-les-neurones\/\" target=\"_blank\" rel=\"noreferrer noopener\">bacteris <\/a>durant el proc\u00e9s d&#8217;<a href=\"https:\/\/ellipse.prbb.org\/ca\/mini-organs-humans-per-estudiar-la-covid-19-i-els-seus-tractaments-de-manera-mes-realista\/\" target=\"_blank\" rel=\"noreferrer noopener\">infecci\u00f3<\/a> dels seus hostes i <strong>crear aix\u00ed noves dianes terap\u00e8utiques.<\/strong><\/p>\n\n\n\n<div style=\"height:32px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u201cAplicar l\u2019an\u00e0lisi de seq\u00fcenciaci\u00f3 massiva en l\u2019estudi de l\u2019activitat gen\u00e8tica durant la infecci\u00f3 \u00e9s un dels m\u00e8todes m\u00e9s accessibles per a descobrir nous tractaments\u201d<br><strong>Benjamin Lang<\/strong>, investigador postdoctoral del CRG i un dels creadors de la base de dades<\/p><\/blockquote>\n\n\n\n<div style=\"height:32px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Davant la situaci\u00f3 actual d&#8217;<strong><a rel=\"noreferrer noopener\" href=\"https:\/\/ellipse.prbb.org\/ca\/els-bacteris-poden-ajudar-se-entre-ells-a-resistir-millor-als-antibiotics\/\" target=\"_blank\">augment de la resist\u00e8ncia bacteriana<\/a><\/strong>, recursos com DualSeqDB ofereixen un <strong>coneixement crucial pel <a href=\"https:\/\/ellipse.prbb.org\/ca\/vols-ajudar-a-resoldre-la-crisi-de-resistencia-als-antibiotics-juga-correctament-les-teves-cartes\/\" target=\"_blank\" rel=\"noreferrer noopener\">futur dels antibi\u00f2tics<\/a>.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>DualSeqDB, creada amb la participaci\u00f3 del CRG i d&#8217;acc\u00e9s obert, permetria a la comunitat cient\u00edfica identificar quins gens utilitzen els bacteris per a infectar i poder desenvolupar aix\u00ed nous f\u00e0rmacs.<\/p>\n","protected":false},"author":9,"featured_media":19156,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[26],"tags":[711,477,261,265,233,679,480,654],"new-type":[35,43],"class_list":["post-19179","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-recerca","tag-antibiotic-ca","tag-bacteris","tag-bioinformatica","tag-crg-ca","tag-farmacologia","tag-infeccio","tag-microorganismes","tag-sequenciacio","new-type-noticies","new-type-recomanem"],"acf":[],"_links":{"self":[{"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/posts\/19179","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/comments?post=19179"}],"version-history":[{"count":6,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/posts\/19179\/revisions"}],"predecessor-version":[{"id":19185,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/posts\/19179\/revisions\/19185"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/media\/19156"}],"wp:attachment":[{"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/media?parent=19179"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/categories?post=19179"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/tags?post=19179"},{"taxonomy":"new-type","embeddable":true,"href":"https:\/\/ellipse.prbb.org\/ca\/wp-json\/wp\/v2\/new-type?post=19179"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}